Motif ID: FOX{I1,J2}.p2

Z-value: 0.866


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ2chr12_+_8185241-0.532.7e-03Click!
FOXI1chr5_+_1695329000.487.8e-03Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_56725982 7.553 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr2_-_135782246 6.807 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr15_-_55800431 6.209 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr12_-_71551564 6.056 TSPAN8
tetraspanin 8
chr12_-_71551778 5.974 NM_004616
TSPAN8
tetraspanin 8
chr12_+_49297892 5.483 NM_033124
CCDC65
coiled-coil domain containing 65
chrX_+_119029799 5.174 NM_001008534
NM_001008535
NM_178813
AKAP14


A kinase (PRKA) anchor protein 14


chr19_-_14992166 5.104 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr12_-_122107559 4.387 NM_173855
MORN3
MORN repeat containing 3
chr19_+_41430123 4.235 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr15_+_78558522 4.185 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chrX_-_44202834 3.598 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chr12_-_25348031 3.568 NM_001082972
NM_001082973
NM_001204101
NM_001204102
NM_018272
CASC1




cancer susceptibility candidate 1




chr4_+_70861647 3.525 NM_001009181
NM_003154
STATH

statherin

chr1_-_151345156 3.414 NM_003944
SELENBP1
selenium binding protein 1
chr4_-_70518964 3.403 NM_001252274
NM_001252275
NM_006798
UGT2A1


UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus


chr5_+_140220811 3.371 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr5_+_10441973 3.098 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr6_+_32407618 3.076 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr9_-_4300028 3.059 NM_001042413
GLIS3
GLIS family zinc finger 3
chr3_-_183273407 2.985 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr4_-_16085666 2.969 PROM1
prominin 1
chr18_+_61370193 2.759 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr16_-_52581713 2.681 NM_001146188
TOX3
TOX high mobility group box family member 3
chr11_+_73661363 2.658 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr16_-_23724820 2.564 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr20_+_43990576 2.374 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr4_+_186350543 2.360 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr13_-_86373328 2.314 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_205538164 2.255 MFSD4
major facilitator superfamily domain containing 4
chr6_+_26501448 2.181 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr4_-_100273831 2.155 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr5_-_110062365 2.141 NM_001039763
TMEM232
transmembrane protein 232
chr16_-_28634873 2.097 NM_177536
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_170335948 2.080 NM_152384
BBS5
Bardet-Biedl syndrome 5
chr13_-_39564857 2.066 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr3_-_57530067 1.937 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr11_-_111944757 1.914 NM_001082619
NM_138789
PIH1D2

PIH1 domain containing 2

chr13_-_36429798 1.865 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr1_-_57045235 1.821 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_167098070 1.818 NM_001199202
NM_001199201
NM_024687
ZBBX


zinc finger, B-box domain containing


chr4_+_72102249 1.805 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_+_104159953 1.789 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr18_-_24765178 1.776 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr18_-_47814691 1.765 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr13_+_36050885 1.741 NM_001204197
NBEA
neurobeachin
chr21_-_43735705 1.721 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr7_+_6617035 1.719 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr20_+_19870209 1.693 NM_018993
RIN2
Ras and Rab interactor 2
chr20_+_9288446 1.684 NM_000933
PLCB4
phospholipase C, beta 4
chr3_-_137893718 1.671 DBR1
debranching enzyme homolog 1 (S. cerevisiae)
chr6_-_52668599 1.583 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr3_+_361365 1.577 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr5_-_35938736 1.555 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr5_+_140247767 1.545 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr7_+_89874487 1.542 NM_001039706
NM_001160138
C7orf63

chromosome 7 open reading frame 63

chr8_-_110657745 1.455 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr16_+_82068958 1.447 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr20_+_9198036 1.444 NM_182797
PLCB4
phospholipase C, beta 4
chr8_+_144640476 1.436 NM_024736
GSDMD
gasdermin D
chr4_+_15471488 1.403 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr6_+_26365397 1.399 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr2_+_38155901 1.390 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr4_-_100212085 1.376 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr3_-_167371288 1.373 NM_178824
WDR49
WD repeat domain 49
chr16_+_82068910 1.357 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr19_+_35629727 1.336 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr3_-_167371701 1.335 WDR49
WD repeat domain 49
chr1_-_77685076 1.328 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr1_-_216978708 1.321 NM_001243514
ESRRG
estrogen-related receptor gamma
chr3_+_151488214 1.315 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr19_+_14491920 1.315 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr16_+_82068830 1.300 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr13_+_24734788 1.294 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr1_+_84764048 1.280 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr21_-_35884503 1.275 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr3_-_114343052 1.270 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_137893636 1.269 DBR1
debranching enzyme homolog 1 (S. cerevisiae)
chr4_+_154178525 1.255 TRIM2
tripartite motif containing 2
chr3_+_93698959 1.247 NM_001174150
NM_001174151
NM_144996
NM_182896
ARL13B



ADP-ribosylation factor-like 13B



chr4_-_69886112 1.242 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr16_-_28620648 1.205 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr9_+_139927515 1.193 C9orf139
chromosome 9 open reading frame 139
chr13_+_43355685 1.192 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr7_+_105603656 1.165 NM_152750
CDHR3
cadherin-related family member 3
chr18_-_53303129 1.135 NM_001243226
TCF4
transcription factor 4
chr11_-_8739398 1.114 ST5
suppression of tumorigenicity 5
chr18_-_47792773 1.112 NM_145020
CCDC11
coiled-coil domain containing 11
chr8_-_110693233 1.111 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr4_+_89299874 1.101 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr12_+_20963637 1.099 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr15_+_45315301 1.094 NM_003104
SORD
sorbitol dehydrogenase
chr6_-_79787784 1.092 PHIP
pleckstrin homology domain interacting protein
chr1_-_57045214 1.088 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_97754147 1.085 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr22_+_46449674 1.077


chr1_+_244214552 1.071 NM_205768
ZNF238
zinc finger protein 238
chr18_-_53177999 1.069 NM_001243231
TCF4
transcription factor 4
chr14_-_20774089 1.068 TTC5
tetratricopeptide repeat domain 5
chr5_+_42550181 1.066 NM_001242405
GHR
growth hormone receptor
chr5_-_176326314 1.065 NM_002115
HK3
hexokinase 3 (white cell)
chr5_+_140165875 1.065 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr17_+_9479943 1.051 NM_001080556
NM_145054
WDR16

WD repeat domain 16

chr19_+_14138959 1.046 NM_080864
RLN3
relaxin 3
chr5_-_111312522 1.043 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr10_-_69597768 1.031 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr16_-_28621279 1.025 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr5_-_121814781 1.012


chr5_+_43609261 0.998 NNT
nicotinamide nucleotide transhydrogenase
chr5_+_140186658 0.987 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr3_-_120400957 0.986 HGD
homogentisate 1,2-dioxygenase
chr4_+_89299980 0.982 HERC6
hect domain and RLD 6
chr1_+_47264669 0.979 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr1_+_47533046 0.977 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr19_-_23456964 0.971 LOC100132815
importin 5 pseudogene
chr6_-_39072412 0.966 C6orf64
chromosome 6 open reading frame 64
chr5_-_41213513 0.963 NM_000065
C6
complement component 6
chr1_-_108231122 0.959 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr12_-_113658826 0.954 NM_138451
IQCD
IQ motif containing D
chr1_+_46646199 0.948 TSPAN1
tetraspanin 1
chr2_-_133429069 0.942 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr11_+_63304272 0.940 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr5_+_140571903 0.940 NM_018930
PCDHB10
protocadherin beta 10
chr6_-_79787887 0.939 PHIP
pleckstrin homology domain interacting protein
chr9_-_89562103 0.936 NM_002048
GAS1
growth arrest-specific 1
chr14_-_20774129 0.935 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr16_+_619905 0.934 NM_004204
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr22_+_24105207 0.927 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr7_-_112726143 0.925 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr6_+_163148163 0.911 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr17_-_38073792 0.908 NM_018530
GSDMB
gasdermin B
chr6_-_52710892 0.899 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr2_+_183943286 0.890 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr6_-_31681845 0.889


chr10_-_116286570 0.882 ABLIM1
actin binding LIM protein 1
chr3_-_121379757 0.881 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_170043608 0.880 NM_001204514
NM_001204516
NM_014970
KIFAP3


kinesin-associated protein 3


chr7_+_48211054 0.877 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr4_-_100356290 0.865 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_84768333 0.864 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr13_+_50589389 0.863 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr4_-_17806820 0.858 DCAF16
DDB1 and CUL4 associated factor 16
chr10_+_70587293 0.857 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr19_+_17337012 0.856 NM_024578
OCEL1
occludin/ELL domain containing 1
chr9_-_88715024 0.855 NM_177937
GOLM1
golgi membrane protein 1
chr3_+_113557679 0.845 NM_017577
GRAMD1C
GRAM domain containing 1C
chr10_+_114154522 0.841 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_50796820 0.837 MYH14
myosin, heavy chain 14, non-muscle
chr13_-_61989654 0.836 NM_022843
PCDH20
protocadherin 20
chr3_-_121379701 0.834 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_141695678 0.833 NM_004668
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr14_+_51026853 0.806 ATL1
atlastin GTPase 1
chr15_+_49462408 0.804 NM_002044
GALK2
galactokinase 2
chr9_-_117267710 0.793 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr16_-_279338 0.786 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr6_-_165723074 0.785 NM_144980
C6orf118
chromosome 6 open reading frame 118
chr11_-_108464344 0.785 NM_015065
EXPH5
exophilin 5
chr3_-_120401401 0.770 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr3_+_171561138 0.766 NM_001164436
TMEM212
transmembrane protein 212
chr1_-_89664510 0.755 NM_052941
GBP4
guanylate binding protein 4
chr16_+_22217369 0.751 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr5_+_156696351 0.740 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_+_244214576 0.735 ZNF238
zinc finger protein 238
chr5_+_159614373 0.735 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr13_+_97794050 0.733 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_61869699 0.730 NFIA
nuclear factor I/A
chr13_-_61989209 0.730 PCDH20
protocadherin 20
chr20_+_58533470 0.725 NM_177980
CDH26
cadherin 26
chr4_+_15704572 0.725 NM_004334
BST1
bone marrow stromal cell antigen 1
chr19_-_9092017 0.724 NM_024690
MUC16
mucin 16, cell surface associated
chr4_-_16085593 0.721 NM_001145847
NM_001145848
PROM1

prominin 1

chr14_+_51026742 0.721 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr4_+_41614911 0.719 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_-_57045129 0.714 PPAP2B
phosphatidic acid phosphatase type 2B
chr11_+_65268313 0.714 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr12_+_131438451 0.707 NM_198827
GPR133
G protein-coupled receptor 133
chr1_-_75139421 0.703 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr17_+_7589388 0.699 NM_001143990
WRAP53
WD repeat containing, antisense to TP53
chr20_+_19915716 0.697 RIN2
Ras and Rab interactor 2
chr22_-_43036606 0.696 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_-_187463474 0.694 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr16_+_10522724 0.693 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr3_-_187454247 0.693 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr7_+_150068252 0.690 NM_014374
REPIN1
replication initiator 1
chr2_+_61389628 0.688 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr9_-_86432546 0.681 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr10_+_118305427 0.676 NM_000936
PNLIP
pancreatic lipase
chr4_-_18023358 0.676 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr9_+_129724503 0.676 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr19_-_58514713 0.673 NM_025027
ZNF606
zinc finger protein 606
chr1_-_217262946 0.670 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chrX_-_117119282 0.670 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr21_-_43346780 0.664 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr19_-_4338750 0.658 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr7_+_121513158 0.656 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr15_-_60919642 0.653 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr1_+_114496498 0.652 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr11_-_5248180 0.651 NM_000518
HBB
hemoglobin, beta
chr3_+_69812961 0.647 NM_006722
MITF
microphthalmia-associated transcription factor
chr2_+_98703594 0.647 NM_144992
VWA3B
von Willebrand factor A domain containing 3B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.50 1.25e-02 GO:0007156 homophilic cell adhesion

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 5.77e-05 GO:0043227 membrane-bounded organelle
1.13 6.18e-05 GO:0043231 intracellular membrane-bounded organelle
1.17 3.51e-03 GO:0005634 nucleus
1.10 3.89e-03 GO:0043229 intracellular organelle
1.10 4.25e-03 GO:0043226 organelle
1.08 4.52e-03 GO:0005622 intracellular
1.08 6.08e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 3.90e-04 GO:0043169 cation binding
1.24 4.17e-04 GO:0046872 metal ion binding
1.24 5.09e-04 GO:0043167 ion binding
1.08 6.94e-03 GO:0005488 binding
1.31 9.63e-03 GO:0008270 zinc ion binding